LONGEVITY MAGAZINE FREE E-JOURNAL
Aging may be inevitable, at least for now, but that doesn’t mean we have to sit back and just let it happen. Increasing lifespan and slowing the aging process has been the focus of much scientific research over the decades and as such a variety of substances have been identified that possess anti-aging properties that may help to decelerate the process.
This is a collection of a few for your review, but keep in mind this is just a short list that is in by no means exhaustive, there are many other supplements that may also offer anti-aging effects.
Curcumin/turmeric has been shown to carry anti-aging properties which have been largely attributed to its potent antioxidant potential. This compound has been demonstrated to activate certain proteins which may help to delay cellular senescence and promote longevity, as well as being associated with a reduced risk of age related mental decline in humans. Additionally it has been shown to combat cellular damage and increase the lifespan of mice, roundworms and fruit flies and postpone age related disease while alleviating the symptoms of age related disease.
EGCG is a polyphenol compound that is found concentrated in green tea that carries some impressive health benefits that are backed by science including reducing the risk of certain cancers and other conditions such as heart disease. Epigallocatechin gallate has an array of potential health promoting properties such as promoting longevity, protecting against age related disease development, restoring mitochondrial function in cells acting on pathways involved in aging, inducing autophagy, as well as being associated with a reduced risk of all cause mortality, diabetes, stroke, and heart disease. Animal studies have shown it to protect against skin aging and wrinkles caused by exposure to UV lighting.
Coenzyme Q10 is an antioxidant produced in the body that plays roles in energy production and protection against cellular damage. However, levels of this decline with age, supplementation has been shown to help improve certain aspects of health in older individuals such as reducing oxidative stress that accelerates the aging process and onset of age related disease.
Nicotinamide riboside and nicotinamide mononucleotide are precursors to nicotinamide adenine dinucleotide which is found in every cell and involved in many critical processes including energy metabolism, DNA repair, and gene expression. However, levels of this also decline with age and it is thought to be associated with accelerated physical decline and the onset of age related disease.
Crocin is a yellow carotenoid pigment in saffron that carries many health benefits including anticancer, anti-inflammatory, anti-anxiety, and antidiabetic effects. It has been studied for its potential to act as an anti-aging agent and ability to protect against age related mental decline. It has been shown to help improve aging in human skin by reducing inflammation and protecting against UV light induced cellular damage. Animal studies have demonstrated prevention against age related nerve damage by inhibiting production of advanced glycation end products and reactive oxygen species that contribute to the aging process.
Resveratrol is a polyphenol that may help to promote longevity by activating sirtuins genes, and it has been shown to increase the lifespan of nematodes, yeasts, and fruit flies. It may help to lower cholesterol, protect brain function, increase insulin sensitivity, ease joint pain, suppress cancer cells, and lengthen lifespan in certain animals.
Quercetin is a natural antioxidant pigment found in many grains, fruits, and vegetables that plays important roles in helping the body combat free radical damage that is linked to chronic diseases. It may help to reduce inflammation, blood pressure, boost immunity, aid exercise performance, reduce allergy symptoms, and help maintain general health.
Fisetin is an antioxidant flavonoid that is a senotherapeutic, which means that it can kill harmful senescent zombie cells. Animal studies suggest that it may help to reduce the number of these cells in tissues to help extend lifespan. It is active against allergic inflammation and has gained attention for its memory enhancing capabilities in animal studies.
These are just a few supplements that might help to slow the aging process and promote a long and healthy life. CoQ10, crocin, festin, curcumin, and NMN are just a few of the compounds that have been shown to offer anti-aging effects in scientific research studies.
While some studies suggest taking supplements may help to slow the aging process the best way to promote longevity and overall health is to follow healthful practices which involves keeping stress in check, getting enough sleep, being physically active, and maintaining a nutritious diet. It is also recommended to consult with your physician or certified medical professional before taking any supplement to avoid possibility of complications.
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