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Some Of The Best Anti-Aging Supplements – Anti Aging News

Esmond Admin — Wed, 15 Dec 2021 07:33:43 +0000

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Aging may be inevitable, at least for now, but that doesn’t mean we have to sit back and just let it happen. Increasing lifespan and slowing the aging process has been the focus of much scientific research over the decades and as such a variety of substances have been identified that possess anti-aging properties that may help to decelerate the process.
This is a collection of a few for your review, but keep in mind this is just a short list that is in by no means exhaustive, there are many other supplements that may also offer anti-aging effects.
Curcumin/turmeric has been shown to carry anti-aging properties which have been largely attributed to its potent antioxidant potential. This compound has been demonstrated to activate certain proteins which may help to delay cellular senescence and promote longevity, as well as being associated with a reduced risk of age related mental decline in humans. Additionally it has been shown to combat cellular damage and increase the lifespan of mice, roundworms and fruit flies and postpone age related disease while alleviating the symptoms of age related disease.
EGCG is a polyphenol compound that is found concentrated in green tea that carries some impressive health benefits that are backed by science including reducing the risk of certain cancers and other conditions such as heart disease. Epigallocatechin gallate has an array of potential health promoting properties such as promoting longevity, protecting against age related disease development, restoring mitochondrial function in cells acting on pathways involved in aging, inducing autophagy, as well as being associated with a reduced risk of all cause mortality, diabetes, stroke, and heart disease. Animal studies have shown it to protect against skin aging and wrinkles caused by exposure to UV lighting.
Coenzyme Q10 is an antioxidant produced in the body that plays roles in energy production and protection against cellular damage. However, levels of this decline with age, supplementation has been shown to help improve certain aspects of health in older individuals such as reducing oxidative stress that accelerates the aging process and onset of age related disease.
Nicotinamide riboside and nicotinamide mononucleotide are precursors to nicotinamide adenine dinucleotide which is found in every cell and involved in many critical processes including energy metabolism, DNA repair, and gene expression. However, levels of this also decline with age and it is thought to be associated with accelerated physical decline and the onset of age related disease.
Crocin is a yellow carotenoid pigment in saffron that carries many health benefits including anticancer, anti-inflammatory, anti-anxiety, and antidiabetic effects. It has been studied for its potential to act as an anti-aging agent and ability to protect against age related mental decline. It has been shown to help improve aging in human skin by reducing inflammation and protecting against UV light induced cellular damage. Animal studies have demonstrated prevention against age related nerve damage by inhibiting production of advanced glycation end products and reactive oxygen species that contribute to the aging process.
Resveratrol is a polyphenol that may help to promote longevity by activating sirtuins genes, and it has been shown to increase the lifespan of nematodes, yeasts, and fruit flies. It may help to lower cholesterol, protect brain function, increase insulin sensitivity, ease joint pain, suppress cancer cells, and lengthen lifespan in certain animals.
Quercetin is a natural antioxidant pigment found in many grains, fruits, and vegetables that plays important roles in helping the body combat free radical damage that is linked to chronic diseases. It may help to reduce inflammation, blood pressure, boost immunity, aid exercise performance, reduce allergy symptoms, and help maintain general health.
Fisetin is an antioxidant flavonoid that is a senotherapeutic, which means that it can kill harmful senescent zombie cells. Animal studies suggest that it may help to reduce the number of these cells in tissues to help extend lifespan. It is active against allergic inflammation and has gained attention for its memory enhancing capabilities in animal studies.
These are just a few supplements that might help to slow the aging process and promote a long and healthy life. CoQ10, crocin, festin, curcumin, and NMN are just a few of the compounds that have been shown to offer anti-aging effects in scientific research studies.
While some studies suggest taking supplements may help to slow the aging process the best way to promote longevity and overall health is to follow healthful practices which involves keeping stress in check, getting enough sleep, being physically active, and maintaining a nutritious diet. It is also recommended to consult with your physician or certified medical professional before taking any supplement to avoid possibility of complications.
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https://www.healthline.com/nutrition/quercetin
https://www.healthline.com/nutrition/resveratrol
https://www.sciencedirect.com/topics/neuroscience/fisetin
https://www.healthline.com/nutrition/anti-aging-supplements

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Resveratrol Supplements: Side Effects and Benefits – WebMD

Esmond Admin — Wed, 15 Dec 2021 07:27:58 +0000

Resveratrol is part of a group of compounds called polyphenols. They’re thought to act like antioxidants, protecting the body against damage that can put you at higher risk for things like cancer and heart disease.
It’s in the skin of red grapes, but you can also find it in peanuts, red wine, berries, and other foods and berries.
Manufacturers have tried to capitalize on its powers by selling resveratrol supplements. Most resveratrol capsules sold in the U.S. contain extracts from an Asian plant called Polygonum cuspidatum. Other resveratrol supplements are made from red wine or red grape extracts.
Ads touting these supplements on the Internet promise everything from weight loss to a healthier, longer life.
Do resveratrol supplements really deliver on those promises?

It’s gained a lot of attention for its reported anti-aging and disease-fighting powers. Researchers have long believed that substances in red wine might have health benefits. Beginning in the 1990s, experts began to focus on resveratrol, an antioxidant compound in red wine. Since then, some animal and lab studies have shown that resveratrol has promising antiviral, anti-inflammatory, and anticancer effects.
It’s important to note that while experts agree that it does have potential, there’s still not enough data to confirm how well it works. Resveratrol supplements have not been well-studied in people. We don’t really know what benefits and risks they might have. We also don’t know if resveratrol is necessarily more important than some of the other natural substances in wine.
Still, early research does suggest it might help protect you against:
Heart disease: It’s thought to help reduce inflammation, lower LDL or “bad” cholesterol, and make it more difficult for clots to form that can lead to a heart attack.
Cancer: It could limit the spread of cancer cells and start killing them.
Alzheimer’s: It may protect nerve cells from damage and fight the plaque buildup that can lead to the disease.
Diabetes: Resveratrol helps prevent insulin resistance, a condition in which the body becomes less sensitive to the blood sugar-lowering hormone insulin. The condition can lead to diabetes.
Researchers believe that resveratrol activates the SIRT1 gene. That gene is believed to protect the body against the effects of obesity and the diseases of aging.
Some people wonder if they should drink more red wine because of the possible health benefits of resveratrol. But most experts and organizations like the American Heart Association still suggest limiting alcoholic drinks to one per day for women and two for men. Four ounces of red wine equals one drink. Other forms of alcohol do not have resveratrol.
So far, studies have not discovered any severe ones, even when resveratrol is taken in large doses. When you get resveratrol in the amount naturally found in foods, it is generally considered safe. It could cause a reaction in those who are allergic to grapes or wine.
People who have health conditions like bleeding disorders should not take resveratrol without talking to a doctor first.
If you take any medicines or other supplements regularly, talk to your health care provider before you start using resveratrol supplements. They could interact with medicines like blood thinners, blood pressure drugs, cancer treatments, MAOI antidepressants, antiviral and antifungal medicines, NSAID painkillers, and supplements like St. John’s wort, garlic, and ginkgo.
As with other supplements, the FDA doesn’t regulate resveratrol. That makes it hard for consumers to know exactly what they’re getting or whether the product is effective. There also isn’t any specific dosage recommendation, and how much you should take can vary from supplement to supplement.
The dosages in most resveratrol supplements are typically much lower than the amounts that research has shown to be helpful. Most supplements contain 250 to 500 milligrams. To get the dose used in some studies, people would have to consume 2 grams of resveratrol (2,000 milligrams) or more a day. Ask your doctor for advice.
Until more high-quality research is done, experts do not recommend resveratrol supplements for antiaging or disease prevention. Resveratrol supplements are also not recommended for children or for women who are pregnant or breastfeeding.
SOURCES:
Brown, L. Alcoholism: Clinical and Experimental Research, 2009.
Linus Pauling Institute: “Resveratrol.”
Baur, J.A. Nature, 2006.
Barger, J.L. PLoS One, 2008.
Memorial Sloan-Kettering Cancer Center: “Resveratrol.”
Van der Spuy, W.J. Nutrition Research Reviews, Sept. 22, 2009.
Karuppagounder, S.S. Neurochemistry International, 2009.
American Heart Association: “Alcohol, Wine and Cardiovascular Disease.”
Fundukian, L., ed. The Gale Encyclopedia of Alternative Medicine, third edition, 2009.
Natural Medicines Comprehensive Database: “Resveratrol.”
Natural Standard Patient Monograph: “Resveratrol.”
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The 12 Best Anti-Aging Supplements – Healthline

Esmond Admin — Wed, 15 Dec 2021 06:42:47 +0000

Aging, which can be defined as the “time-related deterioration of the physiological functions necessary for survival and fertility,” is a process that most people would like to slow (1).
Some of its main causes include accumulated cellular damage caused by reactive molecules known as free radicals and the shortening of telomere, which are the structures located at the ends of chromosomes that play an important role in cellular division (1).
While aging is inevitable, increasing the human lifespan and slowing the aging process has been a focus of scientific research for decades.
Through that research, scientists have identified a large number of substances that have anti-aging properties, many of which can be taken as supplements by those looking for natural ways to decelerate the aging process and prevent age-related disease.
Note that this list is not exhaustive, and many other supplements may also offer anti-aging effects.
Here are 12 supplements with anti-aging properties.
Curcumin — the main active compound in turmeric — has been shown to possess powerful anti-aging properties, which are attributed to its potent antioxidant potential.
Cellular senescence occurs when cells stop dividing. As you age, senescent cells accumulate, which is believed to accelerate aging and disease progression (2, 3).
Research demonstrates that curcumin activates certain proteins, including sirtuins and AMP-activated protein kinase (AMPK), which helps delay cellular senescence and promotes longevity (4, 5).
Plus, curcumin has been shown to combat cellular damage and significantly increase the lifespan of fruit flies, roundworms, and mice. This compound has been shown to postpone age-related disease and alleviate age-related symptoms as well (6, 7).
This may be why turmeric intake has been associated with a reduced risk of age-related mental decline in humans (8).
You can increase your curcumin intake by using turmeric in recipes or taking curcumin supplements.
Curcumin is the main active compound in turmeric. It may slow aging by activating certain proteins and protecting against cellular damage.
Epigallocatechin gallate (EGCG) is a well-known polyphenol compound concentrated in green tea. It offers impressive health benefits, with research supporting its use to reduce the risk of certain cancers, as well as other health conditions like heart disease (9, 10, 11).
Among EGCG’s diverse array of potential health-promoting properties is its ability to promote longevity and protect against age-related disease development.
EGCG may slow aging by restoring mitochondrial function in cells and acting on pathways involved in aging, including the AMP-activated protein kinase signaling pathway (AMPK).
It also induces autophagy, the process by which your body removes damaged cellular material (12).
Green tea intake has been associated with a reduced risk of all-cause mortality, diabetes, stroke, and heart-disease-related death. Plus, animal studies have shown that it can protect against skin aging and wrinkles caused by ultraviolet (UV) light (13, 14, 15).
EGCG can be consumed by drinking green tea or taking concentrated supplements.
EGCG is a polyphenol compound concentrated in green tea that may improve mitochondrial function and promote autophagy. Green tea intake has been linked to a reduced risk of all-cause mortality.
Collagen is promoted as a fountain of youth for its potential to reduce the appearance of skin aging.
It’s an integral component of your skin that helps maintain skin structure. As you age, collagen production slows, leading to collagen loss in the skin that accelerates signs of aging like wrinkles.
Some research suggests that supplementing with collagen may reduce signs of aging, including wrinkles and dry skin.
For example, a 2019 study in 72 women demonstrated that taking a supplement that contained 2.5 grams of collagen — along with several other ingredients, including biotin — per day for 12 weeks significantly improved skin hydration, roughness, and elasticity (16).
Another study in 114 women found that treatment with 2.5 grams of collagen peptides for 8 weeks significantly reduced eye wrinkles and increased collagen levels in the skin (17).
Though these results are promising, keep in mind that many collagen studies are funded by companies that manufacture collagen products, which may influence study results.
Many types of collagen supplements are on the market, including powders and capsules.
Collagen is a popular dietary supplement that may help prevent skin aging by boosting collagen levels in your skin.
Coenzyme Q10 (CoQ10) is an antioxidant that your body produces. It plays essential roles in energy production and protects against cellular damage (18).
Research suggests that levels of CoQ10 decline as you age, and supplementing with it has been shown to improve certain aspects of health in older individuals.
For example, a study in 443 older adults demonstrated that supplementing with CoQ10 and selenium over 4 years improved their overall quality of life, reduced hospital visits, and slowed the deterioration of physical and mental performance (19).
CoQ10 supplements help reduce oxidative stress, a condition characterized by an accumulation of free radicals and other reactive molecules that accelerates the aging process and onset of age-related disease (20, 21).
Though CoQ10 shows promise as an anti-aging supplement, more evidence is needed before it can be recommended as a natural way to delay aging.
Be sure to consult a trusted healthcare professional before giving it a try.
CoQ10 is an important antioxidant that your body naturally produces. Some research shows that supplementing with it may slow age-related physical decline and improve quality of life in older adults.
Nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) are precursors to nicotinamide adenine dinucleotide (NAD+).
NAD+ is a compound found in every cell in your body and involved in many critical processes, including energy metabolism, DNA repair, and gene expression (22, 23).
NAD+ levels decline with age, and this decline is thought to be associated with accelerated physical decline and the onset of age-related diseases like Alzheimer’s (23).
Animal studies have shown that supplementing with NAD+ precursors NMN and NR restores NAD+ levels and prevents age-related physical decline.
For example, a study in aging mice demonstrated that supplementing orally with NMN prevented age-associated genetic changes and improved energy metabolism, physical activity, and insulin sensitivity (24).
Additionally, a 2019 study in 12 men with an average age of 75 showed that supplementing with 1 gram of NR daily for 21 days increased NAD+ levels in skeletal muscle and reduced levels of inflammatory proteins in the body (25).
However, one of the authors in the study above owns stock in and serves as an advisor to the company that manufactured the NR supplement being studied, which may have skewed results (25).
A number of other animal studies have shown positive results related to supplementing with both NR and NMN. However, more human research is needed before strong conclusions on the anti-aging effects of NR and NMN can be made (26, 27).
Supplementing with NMR and NR may help boost NAD+ levels in your body and prevent age-associated genetic changes.
Crocin is a yellow carotenoid pigment in saffron, a popular, pricey spice that’s commonly used in Indian and Spanish cuisine.
Human and animal studies have shown that crocin offers many health benefits, including anticancer, anti-inflammatory, anti-anxiety, and antidiabetic effects (28).
Aside from the properties listed above, crocin has been researched for its potential to act as an anti-aging compound and protect against age-related mental decline (29).
Test-tube and rodent studies have demonstrated that crocin helps prevent age-related nerve damage by inhibiting the production of advanced glycation end products (AGEs) and reactive oxygen species (ROS), which are compounds that contribute to the aging process (30, 31).
Crocin has also been shown to help prevent aging in human skin cells by reducing inflammation and protecting against UV-light-induced cellular damage (32, 33).
Given that saffron is the most expensive spice in the world, a more cost-effective way to boost your crocin intake is by taking a concentrated saffron supplement.
Crocin, which is a pigment found in the spice saffron, shows promise as an anti-aging supplement. It may prevent cellular damage and reduce inflammation, which may promote longevity and prevent mental decline.
Aside from those listed above, the following supplements have impressive anti-aging potential:
Though these results are promising, more research in humans is needed to fully understand how these supplements may be used to promote longevity.
Research has shown that L-theanine, Rhodiola rosea, garlic, Astragalus membranaceus, fisetin, and resveratrol are supplements that may have anti-aging properties.
Certain supplements may help slow the aging process and promote a long, healthy life.
Curcumin, collagen, CoQ10, crocin, nicotinamide mononucleotide, and fesitin are just some of the substances that have been shown to offer anti-aging effects in research studies.
Nevertheless, while some studies suggest that taking certain supplements may help slow aging, the best way to promote longevity and overall health is to engage in healthy practices like consuming a nutritious diet, engaging in regular exercise, and reducing stress.
Last medically reviewed on April 6, 2020
This article is based on scientific evidence, written by experts and fact checked by experts.
Our team of licensed nutritionists and dietitians strive to be objective, unbiased, honest and to present both sides of the argument.
This article contains scientific references. The numbers in the parentheses (1, 2, 3) are clickable links to peer-reviewed scientific papers.

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Maca Root for Curves: Booty-Booster or Bust? – Healthline

Esmond Admin — Wed, 15 Dec 2021 06:39:05 +0000

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Maca is an ingredient that has been extensively studied for its potent health-promoting properties.
It’s also a common supplement used to boost libido, mood, and energy levels.
Additionally, many people claim that maca root can help improve body composition and enhance curviness — despite limited evidence.
This article reviews whether maca root can be used to become curvier.
Maca, also known as Peruvian ginseng or Lepidium meyenii, is an edible plant that is native to Peru.
Classified as a cruciferous vegetable and closely related to plants like broccoli, kale, Brussels sprouts, and cauliflower, it has been well studied for its powerful medicinal properties.
The root of the plant is usually dried and ground into a fine powder, which can be added to smoothies, baked goods, and snacks.
Maca is also available in liquid or capsule form and taken as a supplement to support better health.
In particular, it has been shown to improve sexual function, male fertility, and mood (1, 2, 3).
Maca is a cruciferous vegetable that is used as a supplement and available in powder, liquid, or capsule form.
Currently, no research supports the use of maca root for getting curves.
Nevertheless, it offers some benefits that could help you in this regard when paired with other diet and lifestyle modifications.
Here are a few of the ways that maca may help you become curvier.
Exercise is a key component when it comes to building muscle and getting curves.
Some research suggests that maca may boost physical performance and enhance your exercise routine, which could promote curviness.
For example, a small study in 8 people found that supplementing with maca extract for 14 days improved cycling time compared with a placebo (4).
Similarly, one study showed that administering maca extract to mice for 3 weeks improved endurance and increased the amount of time to exhaustion in a swimming test by up to 41% (5).
In addition to improving endurance and stamina, maca may boost your energy levels to give your workout routine an upgrade.
A 12-week study in 175 people found that taking 3 grams of maca daily led to significant improvements in both mood and energy levels (6).
A study in mice also showed that maca extract helped fight fatigue during a swimming test (7).
Another study even observed that concentrated maca extract relieved fatigue in mice by decreasing several markers of muscle damage during exercise (8).
The above studies demonstrate that maca may help enhance physical performance and fight off fatigue.
This may increase muscle-building, which can help you become curvier.
However, maca alone is unlikely to have any effect on your body composition or curviness unless it’s paired with regular exercise.
Therefore, it’s important to combine your maca supplement with a healthy diet and fitness routine to maximize its possible benefits.
Maca may boost physical performance and energy levels, which could help you get curvier when paired with regular exercise.
Maca has been linked to a number of health benefits, including:
Maca may improve sexual function, male fertility, and memory. It may also reduce symptoms of anxiety and depression.
Maca can be found at a variety of online retailers, natural pharmacies, and health food shops.
Available in powder, liquid, or capsule form, it’s very easy to add to your diet.
Maca root has an earthy, slightly nutty taste and can be included in many recipes. Try adding it to smoothies or mixing it into hot beverages for a quick and convenient way to get your fix.
You can also incorporate it into your favorite baked goods or sprinkle it over oatmeal or yogurt for an added dose of nutrition and health benefits.
Though there’s no official recommended dosage, most studies indicate that 3–5 grams per day are most effective.
Maca is generally considered safe and can be consumed with minimal risk of adverse effects (6).
However, those with thyroid issues should exercise caution when using maca, as it contains goitrogens, which are compounds that could disrupt the production of thyroid hormones in those with thyroid conditions (14).
Additionally, women who are pregnant or breastfeeding should talk to their healthcare practitioner before taking maca, as evidence to support its safety in these populations is insufficient.
Maca is available in powder, liquid, or capsule form and can be added to many foods and drinks. Though it’s generally safe, those with thyroid issues and women who are pregnant or breastfeeding should exercise caution.
Maca is a powerful ingredient that has been linked to various potential health benefits.
Though research to support its use for becoming curvier is lacking, maca root has been shown to increase energy levels and physical performance, which could promote muscle-building and curviness.
Still, it should be paired with regular exercise and a nutritious diet to maximize its potential effects.
This article is based on scientific evidence, written by experts and fact checked by experts.
Our team of licensed nutritionists and dietitians strive to be objective, unbiased, honest and to present both sides of the argument.
This article contains scientific references. The numbers in the parentheses (1, 2, 3) are clickable links to peer-reviewed scientific papers.

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