{"id":10976,"date":"2021-12-15T06:42:47","date_gmt":"2021-12-15T06:42:47","guid":{"rendered":"https:\/\/esmondnaturalusa.com\/2021\/12\/15\/the-12-best-anti-aging-supplements-healthline\/"},"modified":"2021-12-15T08:34:37","modified_gmt":"2021-12-15T08:34:37","slug":"the-12-best-anti-aging-supplements-healthline","status":"publish","type":"post","link":"https:\/\/esmondnaturalusa.com\/the-12-best-anti-aging-supplements-healthline\/","title":{"rendered":"The 12 Best Anti-Aging Supplements – Healthline"},"content":{"rendered":"

Aging, which can be defined as the \u201ctime-related deterioration of the physiological functions necessary for survival and fertility,\u201d is a process that most people would like to slow (1<\/a><\/hl-trusted-source>).
\nSome of its main causes include accumulated cellular damage caused by reactive molecules known as free radicals and the shortening of telomere, which are the structures located at the ends of chromosomes that play an important role in cellular division (1<\/a><\/hl-trusted-source>).
\nWhile aging is inevitable, increasing the human lifespan and slowing the aging process has been a focus of scientific research for decades.
\nThrough that research, scientists have identified a large number of substances that have anti-aging properties, many of which can be taken as supplements by those looking for natural ways to decelerate the aging process and prevent age-related disease.
\nNote that this list is not exhaustive, and many other supplements may also offer anti-aging effects.
\nHere are 12 supplements with anti-aging properties.
\nCurcumin \u2014 the main active compound in turmeric<\/a> \u2014 has been shown to possess powerful anti-aging properties, which are attributed to its potent antioxidant potential.
\nCellular senescence occurs when cells stop dividing. As you age, senescent cells accumulate, which is believed to accelerate aging and disease progression (2<\/a><\/hl-trusted-source>, 3<\/a><\/hl-trusted-source>).
\nResearch demonstrates that curcumin activates certain proteins, including sirtuins and AMP-activated protein kinase (AMPK), which helps delay cellular senescence and promotes longevity (4<\/a><\/hl-trusted-source>, 5<\/a><\/hl-trusted-source>).
\nPlus, curcumin<\/a> has been shown to combat cellular damage and significantly increase the lifespan of fruit flies, roundworms, and mice. This compound has been shown to postpone age-related disease and alleviate age-related symptoms as well (6<\/a><\/hl-trusted-source>, 7<\/a><\/hl-trusted-source>).
\nThis may be why turmeric intake has been associated with a reduced risk of age-related mental decline in humans (8<\/a><\/hl-trusted-source>).
\nYou can increase your curcumin intake by using turmeric in recipes or taking curcumin supplements.
\nCurcumin is the main active compound in turmeric. It may slow aging by activating certain proteins and protecting against cellular damage.
\nEpigallocatechin gallate (EGCG)<\/a> is a well-known polyphenol compound concentrated in green tea. It offers impressive health benefits, with research supporting its use to reduce the risk of certain cancers, as well as other health conditions like heart disease (9<\/a><\/hl-trusted-source>, 10<\/a><\/hl-trusted-source>, 11<\/a><\/hl-trusted-source>).
\nAmong EGCG\u2019s diverse array of potential health-promoting properties is its ability to promote longevity and protect against age-related disease development.
\nEGCG may slow aging by restoring mitochondrial function in cells and acting on pathways involved in aging, including the AMP-activated protein kinase signaling pathway (AMPK).
\nIt also induces autophagy, the process by which your body removes damaged cellular material (12<\/a><\/hl-trusted-source>).
\nGreen tea intake<\/a> has been associated with a reduced risk of all-cause mortality, diabetes, stroke, and heart-disease-related death. Plus, animal studies have shown that it can protect against skin aging and wrinkles caused by ultraviolet (UV) light (13<\/a><\/hl-trusted-source>, 14<\/a><\/hl-trusted-source>, 15<\/a><\/hl-trusted-source>).
\nEGCG can be consumed by drinking green tea or taking concentrated supplements.
\nEGCG is a polyphenol compound concentrated in green tea that may improve mitochondrial function and promote autophagy. Green tea intake has been linked to a reduced risk of all-cause mortality.
\nCollagen is promoted as a fountain of youth for its potential to reduce the appearance of skin aging.
\nIt\u2019s an integral component of your skin that helps maintain skin structure. As you age, collagen production slows, leading to collagen loss in the skin that accelerates signs of aging like wrinkles.
\nSome research suggests that supplementing with collagen<\/a> may reduce signs of aging, including wrinkles and dry skin.
\nFor example, a 2019 study in 72 women demonstrated that taking a supplement that contained 2.5 grams of collagen \u2014 along with several other ingredients, including biotin \u2014 per day for 12 weeks significantly improved skin hydration, roughness, and elasticity (16<\/a><\/hl-trusted-source>).
\nAnother study in 114 women found that treatment with 2.5 grams of collagen peptides for 8 weeks significantly reduced eye wrinkles and increased collagen levels in the skin (17<\/a><\/hl-trusted-source>).
\nThough these results are promising, keep in mind that many collagen studies are funded by companies that manufacture collagen products, which may influence study results.
\nMany types of collagen supplements are on the market, including powders and capsules.
\nCollagen is a popular dietary supplement that may help prevent skin aging by boosting collagen levels in your skin.
\nCoenzyme Q10 (CoQ10)<\/a> is an antioxidant that your body produces. It plays essential roles in energy production and protects against cellular damage (18<\/a><\/hl-trusted-source>).
\nResearch suggests that levels of CoQ10 decline as you age, and supplementing with it has been shown to improve certain aspects of health in older individuals.
\nFor example, a study in 443 older adults demonstrated that supplementing with CoQ10 and selenium over 4 years improved their overall quality of life, reduced hospital visits, and slowed the deterioration of physical and mental performance (19<\/a><\/hl-trusted-source>).
\nCoQ10 supplements help reduce oxidative stress<\/a>, a condition characterized by an accumulation of free radicals and other reactive molecules that accelerates the aging process and onset of age-related disease (20<\/a><\/hl-trusted-source>, 21<\/a><\/hl-trusted-source>).
\nThough CoQ10 shows promise as an anti-aging supplement, more evidence is needed before it can be recommended as a natural way to delay aging.
\nBe sure to consult a trusted healthcare professional before giving it a try.
\nCoQ10 is an important antioxidant that your body naturally produces. Some research shows that supplementing with it may slow age-related physical decline and improve quality of life in older adults.
\nNicotinamide riboside<\/a> (NR) and nicotinamide mononucleotide (NMN) are precursors to nicotinamide adenine dinucleotide (NAD+).
\nNAD+ is a compound found in every cell in your body and involved in many critical processes, including energy metabolism, DNA repair, and gene expression (22<\/a>, 23<\/a><\/hl-trusted-source>).
\nNAD+ levels decline with age, and this decline is thought to be associated with accelerated physical decline and the onset of age-related diseases like Alzheimer\u2019s (23<\/a><\/hl-trusted-source>).
\nAnimal studies have shown that supplementing with NAD+ precursors NMN and NR restores NAD+ levels and prevents age-related physical decline.
\nFor example, a study in aging mice demonstrated that supplementing orally with NMN prevented age-associated genetic changes and improved energy metabolism, physical activity, and insulin sensitivity (24<\/a><\/hl-trusted-source>).
\nAdditionally, a 2019 study in 12 men with an average age of 75 showed that supplementing with 1 gram of NR daily for 21 days increased NAD+ levels in skeletal muscle and reduced levels of inflammatory proteins in the body (25<\/a><\/hl-trusted-source>).
\nHowever, one of the authors in the study above owns stock in and serves as an advisor to the company that manufactured the NR supplement being studied, which may have skewed results (25<\/a><\/hl-trusted-source>).
\nA number of other animal studies have shown positive results related to supplementing with both NR and NMN. However, more human research is needed before strong conclusions on the anti-aging effects of NR and NMN can be made (26<\/a><\/hl-trusted-source>, 27<\/a><\/hl-trusted-source>).
\nSupplementing with NMR and NR may help boost NAD+ levels in your body and prevent age-associated genetic changes.
\nCrocin is a yellow carotenoid pigment in saffron<\/a>, a popular, pricey spice that\u2019s commonly used in Indian and Spanish cuisine.
\nHuman and animal studies have shown that crocin offers many health benefits, including anticancer, anti-inflammatory, anti-anxiety, and antidiabetic effects (28<\/a><\/hl-trusted-source>).
\nAside from the properties listed above, crocin has been researched for its potential to act as an anti-aging compound and protect against age-related mental decline (29<\/a><\/hl-trusted-source>).
\nTest-tube and rodent studies have demonstrated that crocin helps prevent age-related nerve damage by inhibiting the production of advanced glycation end products (AGEs) and reactive oxygen species (ROS), which are compounds that contribute to the aging process (30<\/a><\/hl-trusted-source>, 31<\/a><\/hl-trusted-source>).
\nCrocin has also been shown to help prevent aging in human skin cells by reducing inflammation and protecting against UV-light-induced cellular damage (32<\/a><\/hl-trusted-source>, 33<\/a><\/hl-trusted-source>).
\nGiven that saffron is the most expensive spice in the world, a more cost-effective way to boost your crocin intake is by taking a concentrated saffron supplement.
\nCrocin, which is a pigment found in the spice saffron, shows promise as an anti-aging supplement. It may prevent cellular damage and reduce inflammation, which may promote longevity and prevent mental decline.
\nAside from those listed above, the following supplements have impressive anti-aging potential:
\nThough these results are promising, more research in humans is needed to fully understand how these supplements may be used to promote longevity.
\nResearch has shown that L-theanine, Rhodiola rosea<\/em>, garlic, Astragalus membranaceus<\/em>, fisetin, and resveratrol are supplements that may have anti-aging properties.
\nCertain supplements may help slow the aging process<\/a> and promote a long, healthy life.
\nCurcumin, collagen, CoQ10, crocin, nicotinamide mononucleotide, and fesitin are just some of the substances that have been shown to offer anti-aging effects in research studies.
\nNevertheless, while some studies suggest that taking certain supplements may help slow aging, the best way to promote longevity and overall health is to engage in healthy practices like consuming a nutritious diet, engaging in regular exercise, and reducing stress.
\n Last medically reviewed on April 6, 2020<\/span>
\nThis article is based on scientific evidence, written by experts<\/a> and fact checked by experts.
\nOur team of licensed nutritionists and dietitians strive to be objective, unbiased, honest and to present both sides of the argument.
\nThis article contains scientific references. The numbers in the parentheses (1, 2, 3) are clickable links to peer-reviewed scientific papers.
\nTurmeric is a traditional Indian spice with a powerful compound called curcumin. Here are the top 10 health benefits of turmeric and curcumin.<\/a>
\nNicotinamide riboside \u2014 also called niagen \u2014 supports many aspects of healthy aging. This article reviews nicotinamide riboside, its benefits, side\u2026<\/a>
\nIt’s about time we look as young as we feel. Here’s a simple anti-aging routine, complete with product and ingredient recommendations.<\/a>
\nConsuming collagen may have a variety of health benefits, from relieving joint pain to improving skin health. Here are the top 6 benefits of collagen.<\/a>
\nGreen tea extract is a concentrated supplemental form of green tea. Here are 10 science-based benefits of green tea extract.<\/a>
\nWhich foods are good anti-aging staples? To make sure you have the right amount of protein, veggies, and antioxidant-rich fruits, we compiled this\u2026<\/a>
\nCoenzyme Q10, or CoQ10, is a compound that generates energy in your cells and has a wide range of health benefits. Here are 9 benefits of coenzyme Q10.<\/a>
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Aging, which can be defined as the \u201ctime-related deterioration of the physiological functions necessary for survival and fertility,\u201d is a process that most people would like to slow (1). Some of its main causes include accumulated cellular damage caused by reactive molecules known as free radicals and the shortening of telomere, which are the structures … Continue reading The 12 Best Anti-Aging Supplements – Healthline<\/span><\/a><\/p>\n","protected":false},"author":8,"featured_media":11113,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[489,460],"tags":[],"jetpack_featured_media_url":"https:\/\/esmondnaturalusa.com\/wp-content\/uploads\/2021\/12\/family-700-2.jpg","_links":{"self":[{"href":"https:\/\/esmondnaturalusa.com\/wp-json\/wp\/v2\/posts\/10976"}],"collection":[{"href":"https:\/\/esmondnaturalusa.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/esmondnaturalusa.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/esmondnaturalusa.com\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/esmondnaturalusa.com\/wp-json\/wp\/v2\/comments?post=10976"}],"version-history":[{"count":2,"href":"https:\/\/esmondnaturalusa.com\/wp-json\/wp\/v2\/posts\/10976\/revisions"}],"predecessor-version":[{"id":11114,"href":"https:\/\/esmondnaturalusa.com\/wp-json\/wp\/v2\/posts\/10976\/revisions\/11114"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/esmondnaturalusa.com\/wp-json\/wp\/v2\/media\/11113"}],"wp:attachment":[{"href":"https:\/\/esmondnaturalusa.com\/wp-json\/wp\/v2\/media?parent=10976"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/esmondnaturalusa.com\/wp-json\/wp\/v2\/categories?post=10976"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/esmondnaturalusa.com\/wp-json\/wp\/v2\/tags?post=10976"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}