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Published: Jun 14, 2019
This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20190614005117/en/
Lecture Hall in Shanghai (May 2) (Photo: Business Wire)
With a view to turn productive aging into a worldwide reality, we will continue to grow even further and reinforce NMN research, awareness of the effects of NMN and its commercialization.
Research area
We have conducted the world’s first long-term oral intake of NMN (24 weeks) with the Graduate School of Medical and Dental Health Sciences, National University of Hiroshima, and the interim report of this study has confirmed the appearance of Sirtuin 1 (longevity gene 1) and the increase of many different growth hormones, especially melatonin.
In addition, in order to understand the mechanisms of action of NMN, the non-profit organization The Systems Biology Institute (SBI) (representative: Hiroaki Kitano) has carried out a study called Understanding the Intracellular Mechanism of NMN by Multi-Omics Analysis. Also, National University of Yamaguchi, Joint Faculty of Veterinary Medicine, has started the analysis of the mechanisms of anti-aging symptoms taking companion animals (dogs) as subjects to confirm the control of anti-aging factors. Lastly, we have inaugurated and run our in-house research laboratory in Tokyo, Japan, to further increase the scientific basis of NMN.
Awareness of the effects of NMN
Following the success of the event we organized in December 2018 in Tokyo (Japan), we held a lecture in Shanghai (China) on May 2, 2019.
Chaired by Dr. Hiroaki Kitano, representative of the non-profit corporation The Systems Biology Institute (SBI), we could benefit from lectures by Professor Shin-Ichiro Imai (Thinking about Health- Realization of Productive Aging from the Vanguard of Aging and Lifespan) and Doctor Yoichi Nabeshima (Recent Advances in Aging Research- New Developments in Alzheimer’s Research).
Now we would like to organize such events in many other countries.
We would like to mention that on June 13, the latest research paper by Professor Shin-Ichiro Imai was published in Cell Metabolism.
For more information on the paper, click on the link below:
Title: Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice
For more information about Professor Shin-Ichiro Imai and his research, please click on the link below:
Commercialization area
As a token of our gratitude for all those who have kept an eye on us, and with the intention to reach even further and let new customers try our products, we are launching a thank-you campaign to offer you special discounts for a limited time.
11:00 AM June 14, 2019 – 11:00 AM June 21, 2019 (Tokyo time)
10 % DISCOUNT ON ALL PRODUCTS (from unit price)
You can buy our products on the links below:
Rakuten Global Market
Mirai Lab Official Store
Yahoo! Shopping
What is NMN (β-nicotinamide mononucleotide)?
NMN (β-nicotinamide mononucleotide) is a substance included in the vitamin B3 group, and it is present in all organisms. It is enzyme-based and it can be found in foods such as broccoli and edamame beans, but we cannot replenish our NMN body stock by simple oral ingest. NMN is produced in the body, and it is a coenzyme essential to sustain life.
NMN is converted to NAD+ and acts on the life support center of the hypothalamus, which in turn acts on skeletal muscle, viscera, cells, mitochondria, blood vessels, nerves and response proteins (signal substances) among others, all essential for sustaining life.
NMN is a precursor of NAD+. When NMN acts, it is transformed into NAD+, but even if NAD+ is ingested directly, we cannot obtain the same effects as with NMN. In fact, when NAD+ is ingested, most of it is broken up in the digestive tract.
In addition, direct administration of NAD+ into blood vessels starts a process in which glycogen phosphorylase catalyzes breakdown of glycogen into glucose-1-phosphate, and further into glucose-6-phosphate. Blood glucose level starts to decline (something similar occurs in diabetes.) NAD+ does not pass through the brain barrier, so we cannot expect the effects that we get when we ingest NMN.

View source version on businesswire.com: https://www.businesswire.com/news/home/20190614005117/en/
For inquiries, please contact us on the following e-mail address:
Shinkowa Pharmaceutical Co., Ltd.
Agustin Martin
Tel: +81 3 5405-6393
E-mail: info@shinkowapharma.com
Web: http://shinkowapharma.com/
Source: Shinkowa Pharmaceutical Co., Ltd.
Lecture Hall in Shanghai (May 2) (Photo: Business Wire)
NMN PURE VIP 9000 (Photo: Business Wire)
NMN PURE PREMIUM 6000 (Photo: Business Wire)
NMN Nutraceuticals (supplements) (Photo: Business Wire)
Paper on Cell Metabolism
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